Keep your Desktop clear
With Vista, it is possible to configure Windows Desktop icons to a larger size by visiting the Personalize Control Panel.
While large icons can be useful from time to time, you may well feel you don’t need them enlarged at all times.
To save having to constantly change Desktop settings, hold down the Ctrl key on the keyboard and move the scroll wheel on the mouse - scrolling forwards enlarges icons, while scrolling backwards shrinks them. Icons for older programs may look strange, but the newer Vista icons look very impressive.